New Antidote for Cyanide Found

Cyanide is released in small amounts in cigarette smoke and naturally by some plants like cassava, but when highly concentrated, the chemical compound prevents the cells of the body from using oxygen and becomes a fast-acting poison.

If released during a chemical accident or deployed as a weapon during a terrorist attack, a cloud of cyanide gas could produce a horrifying scene, with victims in desperate need of an antidote. While current treatments for cyanide poisoning could be cumbersome in such a scenario, researchers say they've found an effective antidote that could be administered quickly with an EpiPen-like jab.

Existing cyanide antidotes, which include compounds like hydroxocobalamin, must be administered by an intravenous (IV) infusion so that they can dissolve well enough to be absorbed in the body. But administering an IV infusion requires a certain level of training and equipment, and it could be unwieldy at the scene of a bioterrorist attack.

"You might imagine that you're a paramedic and there are multiple people exposed to cyanide, some of them may be convulsing, it may be very difficult to get the IV line in," researcher Steven Patterson, of the University of Minnesota's Center for Drug Design, told LiveScience.

The solution that Patterson and his colleagues came up with is a substance called sulfanegen TEA, which could be delivered to the body through an intra-muscular (IM) injection, similar to the jab delivered by an epinephrine autoinjector to those suffering a severe allergic reaction.

"The antidote works by taking advantage of our natural biochemical processes, which are able to detoxify cyanide," Patterson explained. "What we do is provide the process present with the material it needs to convert cyanide into thiocyanate," which is much less toxic than cyanide and gets expelled from the body in urine.

The new substance has been tested at toxic, but sublethal, levels on animal models, Patterson said, and further experiments to test the antidote's efficacy against lethal cyanide doses are in the pipeline. The researchers have not observed any adverse events due to the drug during their safety studies, though they don't yet know the upper limits of how much of the antidote a body can safely handle, Patterson said.

The research is funded by the National Institutes of Health's CounterACT program, which seeks to develop medical countermeasures against chemical threat agents. The study was detailed this month in the Journal of Medicinal Chemistry.

Follow LiveScience on Twitter @livescience. We're also on Facebook?& Google+.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/antidote-cyanide-found-132827160.html

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Web/Graphics Design Partner - Graphic Design Forum

Hello everyone here. This is my first post and I believe it is within the forum rules to post this in the category.

After gaining experience in online marketing I am starting an internet marketing firm offering services ranging from SEO to social media marketing. However, I do not have the greatest graphics design or web design expertise. Therefore I am looking to work with quality web and graphic designers in a partnership.

I already have partnerships in place with other marketers in specific fields but have zero partnerships with designers. I am looking for multiple partnerships.

I have a few thoughts on how this would work but would like to speak to some designers and get their feedback. If you are interested in expanding your possible clients and services please contact me.

Joseph

---

Last edited by Buda; Today at 05:59 AM.. Reason: Contact details removed

Source: http://www.graphicdesignforum.com/forum/showthread.php?t=83278

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FTC Chair Announces Resignation One Month After Settling Google Antitrust Case

FTC chairman Jon Leibowitz announced on Thursday that he will resign, one month after the agency reached a settlement with Google after a 20-month investigation into the tech giant's alleged anticompetitive behavior. The resignation had been expected by antitrust lawyers since last summer and will take effect in mid-February. Leibowitz said that he plans to move to the private sector and will likely focus on competition policy and privacy.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/qV9wDL0Vq-M/

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House lawmakers mull path to citizenship for illegal immigrants

WASHINGTON (Reuters) - A bipartisan group in the U.S. House of Representatives is attempting to craft a bill that would give millions of illegal immigrants a way to become citizens, House aides said on Thursday, mirroring an effort in the Senate.

One of the aides said the House legislation would be tougher in some ways than the plan put forward on Monday by four Democrats and four Republicans in the U.S. Senate.

The Senate proposal, which has not yet been put into legislative form, would require illegal immigrants to undergo background checks and pay back taxes and penalties before obtaining temporary legal status in the United States.

The House aide, who requested anonymity, said the House proposal was "tougher in terms of the application process," but would not go into detail.

The House group includes Republicans Mario Diaz-Balart of Florida, John Carter of Texas and Raul Labrador of Idaho, and Democrats Luis Gutierrez of Illinois and Zoe Lofgren from California. The latter is the top Democrat on a House Judiciary subcommittee overseeing immigration.

Another congressional aide said the House legislation was 90 percent complete and included a similar provision to the Senate plan that would make it harder for employers to knowingly hire illegal immigrants.

"We are in touch with our counterparts in the House," New York Democratic Senator Charles Schumer, one of the "Gang of 8" senators who released the Senate proposal on Monday, told a news conference.

"We believe that they're moving along on a set of principles that will be fairly similar to ours, not completely the same."

Any major changes to the immigration law must win support in the Republican-controlled House, where conservatives have in the past rejected what they consider would be an amnesty for those who entered the country illegally.

The fact that the bipartisan group of House lawmakers is likely to include a "path to citizenship" in its proposal is no guarantee that the idea will overcome expected opposition from conservatives, but it could help because it shows some House Republicans are on board.

However, it was unclear on Thursday whether Labrador, one of the House group's newest members, would sign off on the path to citizenship.

"I don't think there should be a new path to citizenship for the adults," Labrador told Reuters. "I Believe that in the House it will be very difficult to pass any bill that has a pathway to citizenship," he said.

Labrador has proposed a program that would allow illegal immigrants who have jobs to apply for temporary but renewable work visas.

The House group, with a membership that has varied, has been meeting privately for about four years. Lawmakers were ready to unveil their immigration legislation in 2012, but shelved the bill because they knew it would not go anywhere in an election year.

(Reporting By Rachelle Younglai; Editing by David Brunnstrom)

Source: http://news.yahoo.com/house-lawmakers-mull-path-citizenship-illegal-immigrants-013734774--business.html

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California restricts hiring after dual-paycheck revelations

SACRAMENTO ? Gov. Jerry Brown's administration has restricted state departments' hiring authority following revelations that hundreds of public employees were receiving pay for second state jobs in addition to their normal salaries.

Workers receiving more than one state paycheck, known in official parlance as "additional appointments," were found in a variety of departments and agencies, including the California Public Employees Retirement System and the Department of Corrections and Rehabilitation, and in several state hospitals.

The Brown administration did not ban the practice, but any such hire must now be approved by its Office of Human Resources.

"It appears that in some cases people were paid additionally for the job they were hired to do in the first place," said Assemblyman Jeff Gorell (R-Camarillo), who introduced a bill Wednesday to ban salaried state employees from holding more than one state job. "It's inappropriate at best and potentially abusive," he said.

Gorell said the proliferation of double paychecks highlights the need for more legislative oversight of the executive branch.

"It's clear that the governor and his administration don't fully understand what's happening in these agencies," he said.

Documents provided by the state controller's office show that 571 nonunion employees hold more than one position in various departments. The records do not show what those employees were paid.

The Sacramento Bee reported that dozens of state corrections officers received additional compensation beyond that of their regular jobs ? some of which paid up to $20,000 per month. The paper also reported that the chief psychiatrist at Napa State Hospital, who receives an annual salary of more than $275,000, was receiving an additional $125 per hour for work as a staff psychiatrist.

"It's a scam," said Jamie Court, president of Consumer Watchdog, a nonprofit advocacy agency. "Many people in all kinds of different jobs work for a set salary understanding that sometimes that means working long hours. Unfortunately, that's not always the culture of government."

A spokesman for the state's largest public employee union said the extra pay was for managers and other nonunion employees who are not eligible for overtime. Most unionized workers receive overtime if they put in extra hours.

A spokesman for CalPERS said it had allowed salaried workers to receive extra pay since June 2011 to help the agency launch and test a new technology project. Brad Pacheco said that using existing workers saved CalPERS an estimated $1.6 million that would have been spent to hire outside consultants and train new staff.

The human resources agency issued a statement saying that officials were "conducting a full review to determine whether there is any justification for continuing this practice."

anthony.york@latimes.com

Source: http://feedproxy.google.com/~r/latimes/news/printedition/opinion/~3/G7uL1CKt9iM/la-me-state-workers-20130131,0,3658372.story

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Michael J. Stover appointed vice president of operations services for Marathon Oil Corporation

Marathon Oil Corporation (NYSE: MRO) announced today that Michael J. Stover, currently manager of the Company?s mid-continent production operations, has been appointed to the newly established position of vice president, Operations Services effective Feb. 1, 2013. In this role, Stover will?have oversight responsibility for Marathon Oil?s Upstream Development, Technology, Technical Excellence, Global Procurement, Land and Commercial Services, and Drilling and Completions activities. Stover will be based in Houston and report to Marathon Oil Corporation chairman, president and CEO Clarence P. Cazalot Jr.?Establishing this new position and capturing the increased organizational alignment associated with it is consistent with our ongoing drive to achieve greater efficiencies throughout Marathon Oil,? said Cazalot. ?Mike possesses a strong blend of operations, technical and planning experience and expertise that will play an important role in our ability to further optimize the contributions of these key services to our continued success.?

Stover earned a Bachelor of Science degree in petroleum and natural gas engineering from Pennsylvania State University in 1986.? He joined Marathon Oil that same year, initially as a roustabout, followed by operations and reservoir engineering assignments for the Yates Field located in West Texas. In 1991, he transferred to the Company?s international group in Houston and was responsible for reservoir and economic studies for fields in Ireland, Tunisia, and Norway. From 1995 thru 2000, Stover was located in Anchorage, Alaska, where he worked both development and exploration projects associated with Marathon Oil?s operations on the Kenai Peninsula.

In 2000, he joined Marathon Oil?s Corporate Strategic Planning group in Houston. In this assignment, his responsibilities included business planning and corporate portfolio modeling to support the reorganization of USX Corporation that lead to the establishment of Marathon Oil Corporation as a standalone company.

Following that assignment Stover relocated to Aberdeen, Scotland, where he held the position of European Business Unit Subsurface and Business Planning Manager. In 2005, he relocated to Houston where assumed the role of East Texas/North Louisiana Asset Manager. In 2006, his area of responsibility was expanded to include Marathon Oil?s Oklahoma oil and gas properties.

In 2009, he assumed the position of Director of Central Evaluation and Financial Planning. In this role, Stover was responsible for providing financial and portfolio analysis across the business enterprise. In late 2011, he assumed his current role of Mid-Continent Asset Manager with responsibility for Marathon Oil?s assets and operations in Oklahoma, East Texas, North Louisiana and Colorado.

Source: Marathon Oil Corporation

To access over 3,000 of the latest oil projects from across the world visit Projects OGP for free trial today

Source: http://www.yourindustrynews.com/blog/?p=17946

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Fewer Americans count on retiring by 65

Jason Reed / Reuters file

Warren Buffett, 82, is among the most high-profile Americans who have continued their careers well past age 65.

By Allison Linn, TODAY

If you?re planning to work past age 65, you may find that you have a surprising amount of company among your peers.

A larger chunk of Americans are working into their late 60s and even beyond, part of a long-term trend that has continued despite the tight job market of the past five years and is expected to increase in coming decades.

?It?s one of the most important changes in the labor force over the last generation,? said Robert Johnson, director of The Urban Institute?s Program on Retirement Policy.

Most Americans?still stop working by the time they hit?65. But about 18.5 percent of Americans age 65 and over were working in 2012, according to the Bureau of Labor Statistics. That?s a nearly 8 percentage point increase from a low in 1985, when just 10.8 percent of Americans over age 65 were still at work.

The trend toward working past age 65 is an about-face from the decades that followed World War II. From the late 1940s through the mid-1980s, the percentage of people over age 65 who were in the labor force generally fell as workers took advantage of pensions and Social Security payments that gave them plenty of financial incentive to quit working by age 62 or even before.

These days, however,?people have an incentive to work longer and wait to collect more lucrative Social Security benefits.

Perhaps more importantly,?more companies have moved from pension-type retirement plans to 401(k)-type plans. Johnson noted 401(k) plans can have the opposite effect on retirement, because they aren?t as generous and provide incentive for people to work longer so they can bulk up their funds more.

?The erosion in traditional pension plans has really encouraged people to work longer,? he said.

Still, not everyone is healthy enough to work past age 65, and many people don?t want to. Alicia Munnell, director of the Center for? Retirement Research at Boston College, said her research has shown that people ages 55 to 64 are more likely to keep working for a few extra years because they didn?t think they could afford to retire.

But she said people who are still working at age 65 and beyond are generally healthier, wealthier and more educated than those who have stopped working, and she thinks a significant chunk are doing so at least partly by choice.

?When you?re talking with people older than 65, people are healthier and better educated and jobs are less physically demanding, and that makes it attractive to stay in the labor force,? she said.

Munnell noted that not all professions are friendly to older workers, so working longer isn't always rewarding or even pleasant. But in some?fields - such as academia -?it is more common and acceptable to stay at work past age 65.

There are also plenty of examples of famous older people, such as Warren Buffett, 82, who are clearly staying on the job more for love than money.?

Related: Are you struggling in the suburbs? We want to hear from you.

The percentage of people 65 and over who are working has continued to increase?in the past five years, even though?the overall labor force participation rate has fallen because the tight job market has made it so hard to find jobs.

Phillip Levine, an economics professor at Wellesley College who has studied retirement trends extensively, said he doesn?t think the recession itself has played a big role in exacerbating the existing trend of older workers staying in the labor force longer.

His research has shown that the Great Recession has?had an opposite effect on many workers who were close to retirement, pushing them into early retirement because they lost a job and couldn?t find a new one.

But in years to come, he does expect the Great Recession will play a role in increasing the number of people who work past age 65. That?s because younger people who were unemployed for several years during this period will then work a few extra years to make up for the earnings, and retirement contributions, they lost during their stints of unemployment.

Johnson, from The Urban Institute, said the continued decline in pension plans also will likely play a role in more people choosing to hold onto their jobs longer than their parents or grandparents.

?The idea of retiring at age 62 ? I think a lot of young people think that?s a quaint idea,? Johnson said.

{"contentId":"16775764","totalVotes":"37246"}

At what age do you plan to retire?

Source: http://lifeinc.today.com/_news/2013/01/30/16775764-fewer-americans-count-on-retiring-by-65?lite

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